Brian Culbertson uses his photographs to raise questions about the depersonalization in modern medicine, where prescription drugs are given out to individuals based on symptoms, regardless of differences in their physical or chemical makeup. Adverse uses both the process and the end result to highlight the danger of this one-size-fits-all approach. Brian creates multi-layered portraits which are printed using the salt print process with prescription medication incorporated into the salt solution. The incorporation of medications used to alter the chemistry of the mind into the salted print process yields unpredictable results with each print - just as it does with our own bodies.

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